PBA Guidebook

PBA Guidebook

PBA Guidebook

The PBA Guidebook will give you the information you need on your Pseudobulbar Affect (PBA) journey, from diagnosis to treatment options. It includes:

PBA 101: Understanding the neurologic condition
How to prepare to talk to your doctor
A journal to track your PBA episodes

Request the guidebook

All fields required unless otherwise noted.

First Name

Last Name

Email

Confirm Email

Would you like to receive the guidebook in the mail? (While supplies last. Can't be mailed to P.O. boxes.)

Yes

No

Address Line 1

Address Line 2 (Optional)

City

State

Zip Code

By providing your mailing address, you agree that you would like to receive information from Otsuka America Pharmaceutical, Inc. (OAPI) related to NUEDEXTA^® (dextromethorphan HBr and quinidine sulfate), including site updates, education, and other OAPI products and services. The information pertaining to you that we collect will be used in accordance with our Privacy Policy.

Download a digital copy

By opting in, I confirm that I am 18 years of age or older and I understand that the information I have provided will be used by Otsuka America Pharmaceutical, Inc. (“Otsuka”) and its contracted third parties to contact me by email and/or direct mail with relevant information, to include participation in market research opportunities. I may also receive relevant information from Otsuka in the future. I will have the ability to opt out from receiving Otsuka communications at any time by calling 1-833-468-7852 or by following the opt-out instruction within the communications.

For more information see our Terms of Use and Privacy Policy.

Do you agree to the terms of use?

Yes: By submitting your information and checking the "Yes" box you agree to the above, as well as OAPI Terms of Use and Privacy Policy.

INDICATION and IMPORTANT SAFETY INFORMATION for NUEDEXTA^® (dextromethorphan HBr and quinidine sulfate)

INDICATION:

NUEDEXTA is approved for the treatment of Pseudobulbar Affect (PBA).

PBA is a medical condition that causes involuntary, sudden, and frequent episodes of crying and/or laughing in people living with certain neurologic conditions or brain injury. PBA episodes are typically exaggerated or don’t match how the person feels. PBA is distinct and different from other types of emotional changes caused by neurologic disease or injury.

NUEDEXTA is only available by prescription.

IMPORTANT SAFETY INFORMATION:

Before you take NUEDEXTA, tell your doctor:

If you are taking monoamine oxidase inhibitors (MAOIs), quinidine, or quinidine-related drugs. These can interact with NUEDEXTA causing serious side effects. MAOIs cannot be taken within 14 days before or after taking NUEDEXTA.
If you have previously had an allergic reaction to dextromethorphan, quinidine or quinidine-like drugs.
About all medicines, herbal supplements, and vitamins you take as NUEDEXTA and certain other medicines can interact causing side effects.
If you have had heart disease or have a family history of heart rhythm problems. NUEDEXTA may cause serious side effects, including changes in heart rhythm. If you have certain heart problems, NUEDEXTA may not be right for you. Your doctor may test your heart rhythm (heartbeats) before you start NUEDEXTA.
If you have myasthenia gravis.

While taking NUEDEXTA, call your doctor right away:

If you feel faint or lose consciousness.
If you experience lightheadedness, chills, fever, nausea, or vomiting as these may be signs of an allergic reaction to NUEDEXTA. Hepatitis has been seen in patients taking quinidine, an ingredient in NUEDEXTA.
If you have unexplained bleeding or bruising. Quinidine, an ingredient in NUEDEXTA, can cause a reduction in the number of platelets in your blood which can be severe and, if left untreated, can be fatal.
If you feel dizzy, since it may increase your risk of falling.
If you have muscle twitching, confusion, high blood pressure, fever, restlessness, sweating, or shivering, as these may be signs of a potential drug interaction called serotonin syndrome.

IMPORTANT SAFETY INFORMATION: (Continued)

While taking NUEDEXTA, call your doctor right away:

If you feel faint or lose consciousness.
If you experience lightheadedness, chills, fever, nausea, or vomiting as these may be signs of an allergic reaction to NUEDEXTA. Hepatitis has been seen in patients taking quinidine, an ingredient in NUEDEXTA.
If you have unexplained bleeding or bruising. Quinidine, an ingredient in NUEDEXTA, can cause a reduction in the number of platelets in your blood which can be severe and, if left untreated, can be fatal.
If you feel dizzy, since it may increase your risk of falling.
If you have muscle twitching, confusion, high blood pressure, fever, restlessness, sweating, or shivering, as these may be signs of a potential drug interaction called serotonin syndrome.

The most common side effects of NUEDEXTA include: diarrhea, dizziness, cough, vomiting, weakness, and swelling of feet and ankles. This is not a complete list of side effects. Tell your doctor about any side effect that bothers you or does not go away.

You are encouraged to report side effects of NUEDEXTA^® (dextromethorphan HBr and quinidine sulfate). Please contact Otsuka America Pharmaceutical, Inc. at 1-800-438-9927 or FDA at 1-800-FDA-10881-800-FDA-1088 (www.fda.gov/medwatch).

Please read FULL PRESCRIBING INFORMATION.

IMPORTANT SAFETY INFORMATION:

If you are taking monoamine oxidase inhibitors (MAOIs), quinidine, or quinidine-related drugs. These can interact with NUEDEXTA causing serious side effects. MAOIs cannot be taken within 14 days before or after taking NUEDEXTA.

If you have previously had an allergic reaction to dextromethorphan, quinidine or quinidine-like drugs.
About all medicines, herbal supplements, and vitamins you take as NUEDEXTA and certain other medicines can interact causing side effects.
If you have had heart disease or have a family history of heart rhythm problems. NUEDEXTA may cause serious side effects, including changes in heart rhythm. If you have certain heart problems, NUEDEXTA may not be right for you. Your doctor may test your heart rhythm (heartbeats) before you start NUEDEXTA.