NUEDEXTA is PROVEN
to reduce PBA EPISODES
PBA (Pseudobulbar Affect) is a medical condition that causes involuntary, sudden, and frequent episodes of crying and/or laughing in people living with certain neurologic conditions or brain injury.
Research in a 12-week clinical trial showed that patients who took the recommended dose of NUEDEXTA had drastic reductions in PBA symptoms and episodes.
compared to 45% on placebo**
in final 2 Weeks
were episode free
compared to 29% on placebo**
Patients taking NUEDEXTA experienced an average of 3.9 less episodes per day compared with 6.8 episodes per day before taking NUEDEXTA. Patients taking placebo experienced an average of 3.0 less episodes per day compared with 4.5 episodes per day before taking placebo.**
*Researchers conducted a 12-week clinical trial. This trial was randomized and double-blind and enrolled 326 patients. NUEDEXTA is the first and only treatment approved by the FDA to treat PBA.
**Pioro EP, Brooks BR, Cummings J, et al. Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect. Ann Neurol. 2010;68:693-702.
PBA affects almost
people in the US who have certain neurologic conditions including Stroke, Alzheimer’s Disease and Dementia, ALS (Lou Gehrig’s Disease), Multiple Sclerosis, and Parkinson’s Disease or Traumatic Brain Injury (TBI).†‡
†Work SS, Colamonico JA, Bradley WG, Kaye RE. Pseudobulbar affect: an under-recognized and under-treated neurological disorder. Adv Ther. 2011;28:586–601.
‡This is not a complete list. Other neurologic conditions have also been associated with PBA.
Because PBA episodes are unpredictable and can happen at inappropriate times, they can leave you feeling misunderstood and frustrated. You might even feel disconnected from the people who care for you. But PBA is treatable. Follow these steps to prepare yourself to talk to the people close to you and to your doctor about PBA and treatment.
Talk to the people close to you
Use the PBA conversation cards to learn how to talk to the people close to you about your crying and/or laughing symptoms. Communication is important in order for both them and you to understand how your symptoms are bothering you and affecting your lives.
Talk to your doctor
Start the conversation about PBA with your doctor. Advocating for yourself is important and doctors want to hear from you so they can help. You can also share your PBA Quiz results.
Ask about NUEDEXTA
If your doctor diagnoses you with PBA, ask if NUEDEXTA could be the right treatment for you. Ask about possible side effects of NUEDEXTA.
Remember, you are your best advocate
When you talk about your PBA episodes, be specific and don’t hold back—the more details you can provide, the easier it will be for your doctor to understand what you are experiencing.
“My whole PBA journey has given me a lot of life lessons, and really strengthened our family because they went through this with me.”
Learn how to take NUEDEXTA and what to expect during treatment, and review important safety information.
See if one of our prescription savings options might be right for you, and discover your patient support options.