Pseudobulbar Affect | NUEDEXTA

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If you or someone you care for suddenly bursts out crying or laughing for no apparent reason, it may be due to a neurologic condition doctors call PseudoBulbar Affect (PBA). PBA is caused by neurologic conditions such as Alzheimer's disease or other dementias, stroke, traumatic brain injury (TBI), Parkinson's disease, multiple sclerosis (MS), or Lou Gehrig's disease (ALS). PBA results in episodes of crying or laughing that are often sudden and exaggerated or do not match what the person is feeling inside. Though frequently mistaken for depression, PBA is thought to be the result of a 'short circuit' in the areas of the brain that control emotional expression. Nearly two million people may have PBA. NUEDEXTA (dextromethorphan hydrobromide and quinidine sulfate) 20mg/10mg capsules is the first and only prescription medicine specifically approved to treat PBA.

In a clinical trial, many patients experienced fewer PBA episodes after the 1st week of taking NUEDEXTA. What’s more, many patients were completely free from PBA episodes at the end of the study. Your results may vary. NUEDEXTA and certain other medicines can interact, causing serious side effects. If you take certain drugs or have certain heart problems, NUEDEXTA may not be right for you. Tell your doctor if you or a family member has ever had any heart disease or problems. These are not all of the possible risks of NUEDEXTA.