NUEDEXTA® (dextromethorphan hydrobromide and quinidine sulfate) 20mg/10mg capsules are approved for the treatment of pseudobulbar affect (PBA). NUEDEXTA and certain other medicines can interact, causing serious side effects. If you take certain drugs or have certain heart problems, NUEDEXTA may not be right for you. These are not all of the possible risks of NUEDEXTA. Click here for more information.
Pseudobulbar Affect | About PBA
About PseudoBulbarAffect - PBA
Sudden, unpredictable episodes of crying or laughing can be a result of a neurologic condition called PseudoBulbar Affect - PBA.
Many people who suffer from PBA describe their episodes as uncontrollable, exaggerated, or different from their true feelings.
PBA can occur when certain neurologic diseases or injuries damage the areas of the brain that control normal expression of emotion. This damage can disrupt brain signaling, causing a ‘short circuit’, which results in episodes of involuntary crying or laughing.
Your doctor may have called PBA by another name, such as pathological crying and laughing or emotional incontinence. Sometimes PBA is mistaken for depression, but unlike depression PBA episodes are sudden, unpredictable and may not truly reflect how a person feels inside.
Who gets PBA?
Although you may not have heard of PBA, it is fairly common. Nearly two million Americans with underlying neurologic diseases or brain injuries are also estimated to suffer from PBA.
PBA can occur in people diagnosed with an underlying neurologic condition such as:
- Alzheimer’s disease or other dementias
- Traumatic brain injury (TBI)
- Parkinson’s disease
- Multiple sclerosis (MS)
- Lou Gehrig’s disease (ALS)