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Real patients living with PBA. Images reflect patients’ health status at the time the images were captured.

is proven to reduce PBA episodes

is proven to reduce PBA episodes

Robert photo

robert image

Robert is a real patient living with PBA. Image reflects patient’s health status at the time the image was captured.

Trying To Make Sense of Your Uncontrollable Crying and/or Laughing?

If you have a neurologic condition or brain injury, such as:

Traumatic brain injury (TBI)
Multiple sclerosis (MS)
Amyotrophic lateral sclerosis (ALS)

Stroke
Alzheimer's disease or dementia
Parkinson's disease

Traumatic brain injury (TBI)
Stroke
Multiple sclerosis (MS)
Alzheimer's disease or dementia
Amyotrophic lateral sclerosis (ALS)
Parkinson's disease

…and you experience sudden, frequent, uncontrollable crying and/or laughing episodes that are exaggerated or don't match how you feel, it's time to learn more about PBA.

Learn More About PBA

Ready To Take the PBA Quiz?

If you think you might have PBA, it’s time to take the PBA Quiz. This 7-question quiz may let you know if the crying and/or laughing episodes you're experiencing are suggestive of PBA.

Take the PBA Quiz

Carol photo

carol mobile image

Carol is a real patient living with PBA. Image reflects patient’s health status at the time the image was captured.

Sequena photo

Sequena photo

Sequena is a real patient living with PBA. Image reflects patient’s health status at the time the image was captured.

Ready To Talk to a Doctor About Treatment?

NUEDEXTA is PROVEN to reduce PBA episodes. Learn more about treatment for PBA and access support and co-pay card savings to help you in your treatment journey.

Learn How To Treat PBA

You Are Not Alone.
Connect With Real Patients.

Hear from other patients living with PBA and taking NUEDEXTA.

Individual results vary. All ambassadors are real patients living with PBA or caregivers for real patients living with PBA. Images reflect patients’ health status at the time the images were captured.

Meet Real Patients

INDICATION and IMPORTANT SAFETY INFORMATION for NUEDEXTA^® (dextromethorphan HBr and quinidine sulfate)

INDICATION:

NUEDEXTA is approved for the treatment of Pseudobulbar Affect (PBA).

PBA is a medical condition that causes involuntary, sudden, and frequent episodes of crying and/or laughing in people living with certain neurologic conditions or brain injury. PBA episodes are typically exaggerated or don’t match how the person feels. PBA is distinct and different from other types of emotional changes caused by neurologic disease or injury.

NUEDEXTA is only available by prescription.

IMPORTANT SAFETY INFORMATION:

Before you take NUEDEXTA, tell your doctor:

If you are taking monoamine oxidase inhibitors (MAOIs), quinidine, or quinidine-related drugs. These can interact with NUEDEXTA causing serious side effects. MAOIs cannot be taken within 14 days before or after taking NUEDEXTA.
If you have previously had an allergic reaction to dextromethorphan, quinidine or quinidine-like drugs.
About all medicines, herbal supplements, and vitamins you take as NUEDEXTA and certain other medicines can interact causing side effects.
If you have had heart disease or have a family history of heart rhythm problems. NUEDEXTA may cause serious side effects, including changes in heart rhythm. If you have certain heart problems, NUEDEXTA may not be right for you. Your doctor may test your heart rhythm (heartbeats) before you start NUEDEXTA.
If you have myasthenia gravis.

While taking NUEDEXTA, call your doctor right away:

If you feel faint or lose consciousness.
If you experience lightheadedness, chills, fever, nausea, or vomiting as these may be signs of an allergic reaction to NUEDEXTA. Hepatitis has been seen in patients taking quinidine, an ingredient in NUEDEXTA.
If you have unexplained bleeding or bruising. Quinidine, an ingredient in NUEDEXTA, can cause a reduction in the number of platelets in your blood which can be severe and, if left untreated, can be fatal.
If you feel dizzy, since it may increase your risk of falling.
If you have muscle twitching, confusion, high blood pressure, fever, restlessness, sweating, or shivering, as these may be signs of a potential drug interaction called serotonin syndrome.

IMPORTANT SAFETY INFORMATION: (Continued)

While taking NUEDEXTA, call your doctor right away:

If you feel faint or lose consciousness.
If you experience lightheadedness, chills, fever, nausea, or vomiting as these may be signs of an allergic reaction to NUEDEXTA. Hepatitis has been seen in patients taking quinidine, an ingredient in NUEDEXTA.
If you have unexplained bleeding or bruising. Quinidine, an ingredient in NUEDEXTA, can cause a reduction in the number of platelets in your blood which can be severe and, if left untreated, can be fatal.
If you feel dizzy, since it may increase your risk of falling.
If you have muscle twitching, confusion, high blood pressure, fever, restlessness, sweating, or shivering, as these may be signs of a potential drug interaction called serotonin syndrome.

The most common side effects of NUEDEXTA include: diarrhea, dizziness, cough, vomiting, weakness, and swelling of feet and ankles. This is not a complete list of side effects. Tell your doctor about any side effect that bothers you or does not go away.

You are encouraged to report side effects of NUEDEXTA^® (dextromethorphan HBr and quinidine sulfate). Please contact Otsuka America Pharmaceutical, Inc. at 1-800-438-9927 or FDA at 1-800-FDA-10881-800-FDA-1088 (www.fda.gov/medwatch).

Please read FULL PRESCRIBING INFORMATION.

IMPORTANT SAFETY INFORMATION:

If you are taking monoamine oxidase inhibitors (MAOIs), quinidine, or quinidine-related drugs. These can interact with NUEDEXTA causing serious side effects. MAOIs cannot be taken within 14 days before or after taking NUEDEXTA.

If you have previously had an allergic reaction to dextromethorphan, quinidine or quinidine-like drugs.
About all medicines, herbal supplements, and vitamins you take as NUEDEXTA and certain other medicines can interact causing side effects.
If you have had heart disease or have a family history of heart rhythm problems. NUEDEXTA may cause serious side effects, including changes in heart rhythm. If you have certain heart problems, NUEDEXTA may not be right for you. Your doctor may test your heart rhythm (heartbeats) before you start NUEDEXTA.