Please see below for Important Safety Information and Full Prescribing Information.

NUEDEXTA can interact with other medications, causing serious side effects or changes in how your medications or NUEDEXTA may affect you.

Before taking NUEDEXTA, tell your doctor about all medications and supplements you are taking before taking NUEDEXTA. While taking NUEDEXTA, do not start any new medications without first talking with your doctor. Ask your doctor what medications you cannot use with NUEDEXTA. Tell your doctor if you have heart disease, or if you or a family member have ever had any heart rhythm problems.

The most common side effects of NUEDEXTA include: 

  • diarrhea
  • dizziness
  • cough
  • vomiting
  • weakness 
  • swelling of feet and ankles

Each of these side effects was seen in <15% of the 107 patients who received NUEDEXTA in a clinical trial. These are not all the possible risks of NUEDEXTA. Tell your doctor about any side effect that bothers you or does not go away.

An allergic reaction to NUEDEXTA could occur. Seek medical attention immediately if you develop symptoms of an allergic reaction such as:

  • swelling of the throat and tongue
  • difficulty breathing
  • abnormal heart rate or rhythm (arrhythmia) 
  • dizziness
  • fever
  • rash
  • hives after taking NUEDEXTA

While taking NUEDEXTA, call your doctor right away:

  • If you feel faint or lose consciousness.
  • If you experience lightheadedness, chills, fever, nausea, or vomiting as these may be signs of an allergic reaction to NUEDEXTA. Hepatitis has been seen in patients taking quinidine, an ingredient in NUEDEXTA.
  • If you have unexplained bleeding or bruising. Quinidine, an ingredient in NUEDEXTA, can cause a reduction in the number of platelets in your blood which can be severe and, if left untreated, can be fatal.
  • If you feel dizzy, since it may increase your risk of falling.
  • If you have muscle twitching, confusion, high blood pressure, fever, restlessness, sweating, or shivering, as these may be signs of a potential drug interaction called serotonin syndrome.

NUEDEXTA may cause dizziness. If you feel dizzy, be extra careful not to fall, especially if you have a hard time walking or a problem with falling.

Tell your doctor about any side effect that bothers you or does not go away.